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HIV-1 Nef-induced lncRNA AK006025 regulates CXCL9/10/11 cluster gene expression in astrocytes through interaction with CBP/P300

BACKGROUND: HIV-associated neurocognitive disorder (HAND) is a neurodegenerative disease associated with persistent neuroinflammation and subsequent neuron damage. Pro-inflammatory factors and neurotoxins from activated astrocytes by HIV-1 itself and its encoded proteins, including the negative fact...

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Detalles Bibliográficos
Autores principales: Zhou, Feng, Liu, Xiaomei, Zuo, Dongjiao, Xue, Min, Gao, Lin, Yang, Ying, Wang, Jing, Niu, Liping, Cao, Qianwen, Li, Xiangyang, Hua, Hui, Zhang, Bo, Hu, Minmin, Gao, Dianshuai, Zheng, Kuiyang, Izumiya, Yoshihiro, Tang, Renxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208068/
https://www.ncbi.nlm.nih.gov/pubmed/30382871
http://dx.doi.org/10.1186/s12974-018-1343-x