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Elevated IL-33 promotes expression of MMP2 and MMP9 via activating STAT3 in alveolar macrophages during LPS-induced acute lung injury

BACKGROUND: Pulmonary inflammation and endothelial barrier permeability increase in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) induced by pro-inflammatory cytokines and matrix metalloproteinases (MMPs). However, the relationship between pro-inflammatory cytokines and MMPs...

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Detalles Bibliográficos
Autores principales: Liang, Yafeng, Yang, Nengli, Pan, Guoquan, Jin, Bingxin, Wang, Shufen, Ji, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208075/
https://www.ncbi.nlm.nih.gov/pubmed/30410547
http://dx.doi.org/10.1186/s11658-018-0117-x