Chronic Alcohol Treatment-Induced GABA-Aα5 Histone H3K4 Trimethylation Upregulation Leads to Increased GABA-Aα5 Expression and Susceptibility to Alcohol Addiction in the Offspring of Wistar Rats

Gamma-aminobutyric acid (GABA)-Aα5 is considered to be associated with alcohol-induced memory deficits. However, whether it participates in the formation of alcohol addiction or in the regulation of its susceptibility is unknown. Here, we used a chronic alcohol treatment model to obtain alcohol-addi...

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Detalles Bibliográficos
Autores principales: Zeng, Kuan, Xie, Aimin, Zhang, Xiaojie, Zhong, Baoliang, Liu, Xuebing, Hao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208097/
https://www.ncbi.nlm.nih.gov/pubmed/30405449
http://dx.doi.org/10.3389/fpsyt.2018.00468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208097/
https://www.ncbi.nlm.nih.gov/pubmed/30405449
http://dx.doi.org/10.3389/fpsyt.2018.00468

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