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Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells
BACKGROUND: Transcriptional profiling with ultra-low input methods can yield valuable insights into disease, particularly when applied to the study of immune cells using RNA-sequencing. The advent of these methods has allowed for their use in profiling cells collected in clinical trials and other st...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208098/ https://www.ncbi.nlm.nih.gov/pubmed/30376808 http://dx.doi.org/10.1186/s12865-018-0268-6 |