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Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial

BACKGROUND: Trauma is the leading cause of morbidity and mortality in children in the United States. The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage, however, the drug has not been evaluated in a clinical trial in severely injured children. We de...

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Detalles Bibliográficos
Autores principales: Nishijima, Daniel K., VanBuren, John, Hewes, Hilary A., Myers, Sage R., Stanley, Rachel M., Adelson, P. David, Barnhard, Sarah E., Bobinski, Matthew, Ghetti, Simona, Holmes, James F., Roberts, Ian, Schalick, Walton O., Tran, Nam K., Tzimenatos, Leah S., Michael Dean, J., Kuppermann, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208101/
https://www.ncbi.nlm.nih.gov/pubmed/30376893
http://dx.doi.org/10.1186/s13063-018-2974-z