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The Roles of NRF2 in Modulating Cellular Iron Homeostasis

Significance: Iron and oxygen are intimately linked: iron is an essential nutrient utilized as a cofactor in enzymes for oxygen transport, oxidative phosphorylation, and metabolite oxidation. However, excess labile iron facilitates the formation of oxygen-derived free radicals capable of damaging bi...

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Detalles Bibliográficos
Autores principales: Kerins, Michael John, Ooi, Aikseng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208163/
https://www.ncbi.nlm.nih.gov/pubmed/28793787
http://dx.doi.org/10.1089/ars.2017.7176