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The Roles of NRF2 in Modulating Cellular Iron Homeostasis
Significance: Iron and oxygen are intimately linked: iron is an essential nutrient utilized as a cofactor in enzymes for oxygen transport, oxidative phosphorylation, and metabolite oxidation. However, excess labile iron facilitates the formation of oxygen-derived free radicals capable of damaging bi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Mary Ann Liebert, Inc., publishers
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208163/ https://www.ncbi.nlm.nih.gov/pubmed/28793787 http://dx.doi.org/10.1089/ars.2017.7176 |