N-glycan Remodeling Using Mannosidase Inhibitors to Increase High-mannose Glycans on Acid α-Glucosidase in Transgenic Rice Cell Cultures

Glycoengineering of plant expression systems is a prerequisite for the production of biopharmaceuticals that are compatible with animal-derived glycoproteins. Large amounts of high-mannose glycans such as Man(7)GlcNAc(2), Man(8)GlcNAc(2), and Man(9)GlcNAc(2) (Man7/8/9), which can be favorably modifi...

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Detalles Bibliográficos
Autores principales: Choi, Hong-Yeol, Park, Heajin, Hong, Jong Kwang, Kim, Sun-Dal, Kwon, Jun-Young, You, SeungKwan, Do, Jonghye, Lee, Dong-Yup, Kim, Ha Hyung, Kim, Dong-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208381/
https://www.ncbi.nlm.nih.gov/pubmed/30382146
http://dx.doi.org/10.1038/s41598-018-34438-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208381/
https://www.ncbi.nlm.nih.gov/pubmed/30382146
http://dx.doi.org/10.1038/s41598-018-34438-z

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