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Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen

Aerotaxis or chemotaxis to oxygen was described in bacteria 130 years ago. In eukaryotes, the main adaptation to hypoxia currently described relies on HIF transcription factors. To investigate whether aerotaxis is conserved in higher eukaryotes, an approach based on the self-generation of hypoxia af...

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Detalles Bibliográficos
Autores principales: Deygas, Mathieu, Gadet, Rudy, Gillet, Germain, Rimokh, Ruth, Gonzalo, Philippe, Mikaelian, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208388/
https://www.ncbi.nlm.nih.gov/pubmed/30382089
http://dx.doi.org/10.1038/s41467-018-06988-3