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The HCV genome domains 5BSL3.1 and 5BSL3.3 act as managers of translation

The RNA genome of the hepatitis C virus (HCV) encodes a single open reading frame (ORF) containing numerous functional elements. Among these, the cis-acting replication element (CRE) at the 3′ end of the viral ORF, has become of increasing interest given its dual role as a viral translation represso...

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Detalles Bibliográficos
Autores principales: Romero-López, Cristina, Ríos-Marco, Pablo, Berzal-Herranz, Beatriz, Berzal-Herranz, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208389/
https://www.ncbi.nlm.nih.gov/pubmed/30382192
http://dx.doi.org/10.1038/s41598-018-34422-7