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Cardiac troponins may be irreversibly modified by glycation: novel potential mechanisms of cardiac performance modulation

Dynamic movements of the cardiac troponin complex are an important component of the cardiac cycle. Whether cardiac troponins are subjected to irreversible advanced glycation end-product (AGE) modification is unknown. This study interrogated human and rat cardiac troponin-C, troponin-I and troponin-T...

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Detalles Bibliográficos
Autores principales: Janssens, Johannes V., Ma, Brendan, Brimble, Margaret A., Van Eyk, Jennifer E., Delbridge, Lea M. D., Mellor, Kimberley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208411/
https://www.ncbi.nlm.nih.gov/pubmed/30382112
http://dx.doi.org/10.1038/s41598-018-33886-x