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Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation

Yes-associated protein (YAP) is a mechanosensor protein and a downstream effector of the Hippo kinase pathway, which controls organ growth, cell proliferation, survival, maintenance and regeneration. Unphosphorylated YAP translocates to the nucleus where it acts as a cofactor of primarily the TEAD t...

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Detalles Bibliográficos
Autores principales: Corley, Susan M., Mendoza-Reinoso, Veronica, Giles, Nichole, Singer, Emma Suwanun, Common, John E., Wilkins, Marc R., Beverdam, Annemiek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208416/
https://www.ncbi.nlm.nih.gov/pubmed/30382077
http://dx.doi.org/10.1038/s41419-018-1141-5