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Functional polarization of human hepatoma HepaRG cells in response to forskolin

HepaRG is an original human hepatoma cell line, acquiring highly differentiated hepatic features when exposed to dimethylsulfoxide (DMSO). To search alternatives to DMSO, which may exert some toxicity, we have analyzed the effects of forskolin (FSK), a cAMP-generating agent known to favor differenti...

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Detalles Bibliográficos
Autores principales: Mayati, Abdullah, Moreau, Amélie, Le Vée, Marc, Bruyère, Arnaud, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208432/
https://www.ncbi.nlm.nih.gov/pubmed/30382126
http://dx.doi.org/10.1038/s41598-018-34421-8