Cargando…

A placebo-controlled efficacy study of the intravesical immunomodulators TMX-101 and TMX-202 in an orthotopic bladder cancer rat model

PURPOSE: TMX-101 and TMX-202 are formulations of toll-like receptor 7 (TLR-7) agonists, under investigation for the treatment of urothelial carcinoma. Our goal was to evaluate the efficacy of intravesical instillations of TMX-101 or TMX-202 in an orthotopic bladder cancer rat model. METHODS: Four gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Falke, Johannes, Hulsbergen-van de Kaa, Christina A., Maj, Roberto, Oosterwijk, Egbert, Witjes, J. Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208681/
https://www.ncbi.nlm.nih.gov/pubmed/29767328
http://dx.doi.org/10.1007/s00345-018-2334-3