Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease

Of all of the neuropathological changes observed in Alzheimer’s disease (AD), the loss of synapses correlates most strongly with cognitive decline. The precise mechanisms of synapse degeneration in AD remain unclear, although strong evidence indicates that pathological forms of both amyloid beta and...

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Detalles Bibliográficos
Autores principales: Pickett, Eleanor K., Rose, Jamie, McCrory, Caoimhe, McKenzie, Chris-Anne, King, Declan, Smith, Colin, Gillingwater, Thomas H., Henstridge, Christopher M., Spires-Jones, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208730/
https://www.ncbi.nlm.nih.gov/pubmed/30191401
http://dx.doi.org/10.1007/s00401-018-1903-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208730/
https://www.ncbi.nlm.nih.gov/pubmed/30191401
http://dx.doi.org/10.1007/s00401-018-1903-2

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