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Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease
Of all of the neuropathological changes observed in Alzheimer’s disease (AD), the loss of synapses correlates most strongly with cognitive decline. The precise mechanisms of synapse degeneration in AD remain unclear, although strong evidence indicates that pathological forms of both amyloid beta and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208730/ https://www.ncbi.nlm.nih.gov/pubmed/30191401 http://dx.doi.org/10.1007/s00401-018-1903-2 |