Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

The ordered assembly of tau protein into abnormal filaments is a defining characteristic of Alzheimer’s disease (AD) and other neurodegenerative disorders. It is not known if the structures of tau filaments vary within, or between, the brains of individuals with AD. We used a combination of electron...

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Detalles Bibliográficos
Autores principales: Falcon, Benjamin, Zhang, Wenjuan, Schweighauser, Manuel, Murzin, Alexey G., Vidal, Ruben, Garringer, Holly J., Ghetti, Bernardino, Scheres, Sjors H. W., Goedert, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208733/
https://www.ncbi.nlm.nih.gov/pubmed/30276465
http://dx.doi.org/10.1007/s00401-018-1914-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208733/
https://www.ncbi.nlm.nih.gov/pubmed/30276465
http://dx.doi.org/10.1007/s00401-018-1914-z

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