Cargando…

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

In Alzheimer’s disease (AD) and other tauopathies, the cytosolic protein Tau misfolds and forms intracellular aggregates which accumulate within the brain leading to neurodegeneration. Clinical progression is tightly linked to the progressive spread of Tau pathology throughout the brain, and several...

Descripción completa

Detalles Bibliográficos
Autores principales:	Courade, Jean-Philippe, Angers, Rachel, Mairet-Coello, Georges, Pacico, Nathalie, Tyson, Kerry, Lightwood, Daniel, Munro, Rebecca, McMillan, David, Griffin, Robert, Baker, Terry, Starkie, Dale, Nan, Ruodan, Westwood, Marta, Mushikiwabo, Marie-Laetitia, Jung, Sophie, Odede, Geofrey, Sweeney, Berni, Popplewell, Andrew, Burgess, Gillian, Downey, Patrick, Citron, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208734/ https://www.ncbi.nlm.nih.gov/pubmed/30238240 http://dx.doi.org/10.1007/s00401-018-1911-2

Ejemplares similares

Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody
por: Albert, Marie, et al.
Publicado: (2019)

From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy
por: Colin, Morvane, et al.
Publicado: (2019)

A cell-based model of pathological tau uptake and propagation
por: Falcon, Ben, et al.
Publicado: (2013)

Analysis of clinical failure of anti-tau and anti-synuclein antibodies in neurodegeneration using a quantitative systems pharmacology model
por: Geerts, Hugo, et al.
Publicado: (2023)

Updated Measurement of the \tau Polarisation in \tau -> \tau(K)\nu_\tau
por: Moraes, D, et al.
Publicado: (1998)

Search for the decays $B_s^0\to\tau^+\tau^-$ and $B^0\to\tau^+\tau^-$
por: Aaij, Roel, et al.
Publicado: (2017)

Measurement of sigma_tau+ tau- and A^tau+ tau- _FB with '92 data
por: Ganis, G, et al.
Publicado: (1994)

$Z \to \tau\tau$ and $W \to \tau\nu_\tau$ Cross-Sections at the LHC
por: Ilten, Philip
Publicado: (2012)

Tau at CMS (From Tau Lepton and Tau in SM measurements to Tau Role in Discovery)
por: Mohammadi, Abdollah
Publicado: (2012)

Higgs to tau tau (MSSM)
por: CMS Collaboration
Publicado: (2013)

Higgs to tau tau at the LHC
por: Farrington, SM
Publicado: (2013)

Search for Higgs boson pairs decaying to WWWW, WW$\tau\tau$, and $\tau\tau\tau\tau$ in proton-proton collisions at $\sqrt{s} = $ 13 TeV
por: Tumasyan, Armen, et al.
Publicado: (2022)

Measurement of the tau polarization in Z$^{0}$ --> $\tau^{+}\tau^{-}$ decay
por: Gómez-Cadenas, J J
Publicado: (1992)

$H\to \tau^{+}\tau^{-}$ and $H^{\pm} \to \tau^{\pm}\nu_{\tau}$ with the ATLAS detector at the LHC
por: Gonçalo, R
Publicado: (2010)

Library of anomalous $\tau\tau\gamma$ couplings for $\tau^{+} \tau^{-} (n \gamma)$ Monte Carlo programs
por: Paul, Thomas Cantzon, et al.
Publicado: (1999)

Preliminary results on sigma_tau+ tau- and A^tau+ tau-_FB with '93 data (For Summer Conferences)
por: Ganis, G, et al.
Publicado: (1994)

The $\tau$-polarisation test for the $H/A \to \tau^{+}\tau^{-}$ signal at the LHC
por: Moretti, S., et al.
Publicado: (2002)

Correlation measurements in $Z \rightarrow \tau^{+}\tau^{-}$ and the $\tau$ neutrino helicity
por: Buskulic, Damir, et al.
Publicado: (1993)

Study of H -> Tau Tau with Hadronic Tau Decays in CMS
por: Kinnunen, Ritva, et al.
Publicado: (2003)

$Z \to \tau \tau$ and $W \to \tau \nu$ Cross-Sections at LHC
por: Ilten, P
Publicado: (2012)

Determination of the structure of $\tau$ decays in the reaction e+e- --> $\tau^{+}\tau^{-}$ --> $\varrho^{+}\overline{\nu}_{\tau}\varrho$ $^{-}\nu_{\tau}$ and a precision measurement of the $\tau$-neutrino helicity
por: Albrecht, H, et al.
Publicado: (1994)

Measurement of $\tau$ production and decay parameters with the process $e^{+}e^{-} \to Z^{0} \to \tau^{+}\tau^{-} \tau \to $\mu\nu_{\tau}\nu_{\mu}$
por: Roehn, S
Publicado: (1991)

On the Lorentz Structure of Z --> tau tau
por: Stiegler, U
Publicado: (1992)

Tau physics and tau-charm factories
por: Pich, Antonio
Publicado: (1993)

H --> $\tau^{+}\tau^{-}$ detection at LHC
por: Di Lella, L
Publicado: (1990)

Higgs to tau tau (SM) (HCP)
por: CMS Collaboration
Publicado: (2012)

On the Magnetic Moment in Z --> tau-tau
por: Stiegler, U
Publicado: (1992)

Improved Z --> tau+ tau- selection
por: Ganis, G, et al.
Publicado: (1993)

Higgs to tau tau (MSSM) (HCP)
por: CMS Collaboration
Publicado: (2012)

Higgs to tau tau measurements with CMS
por: Hlushchenko, Olena
Publicado: (2020)

Measurement of mass difference between \tau^- and \tau^+ and mass of \tau -neutrino from three-prong \tau -decays
por: Chapkin, M, et al.
Publicado: (1996)

Reconstruction of $m_{A}$ in $A^{0}\to\tau\tau\to l^{pm}+\tau$ jet $+R^{miss}_{\tau}$
por: Kinnunen, Ritva
Publicado: (1997)

Measurement of mass difference between $\tau^{-}$ and $\tau^{+}$ and mass of $\tau$-neutrino from three-prong $\tau$-decays
por: Chapkin, M M
Publicado: (1998)

Measurement of the Michel parameters and the average $\tau$ neutrino helicity from $\tau$ decays in $e^{+}e^{-} \to \tau^{+}\tau^{-}$
por: Acciarri, M, et al.
Publicado: (1996)

Measurement of $D_{s}^{-} \to \tau^{-}\overline{\nu}_\tau$ and a New Limit for $B^- \to \tau^{- }\overline{\nu}_\tau$
por: Acciarri, M, et al.
Publicado: (1996)

Measurement of the Branching Ratios for b- tau- nu_tau X and b - D*+ tau- nu_tau (X)
por: CERN. Geneva
Publicado: (1996)

$\tau _{B_{s}}/\tau _{B_{d}}$ and $\Delta \Gamma _{s}$ confront new physics in $b\rightarrow s\tau \tau $
por: Bordone, Marzia, et al.
Publicado: (2023)

Search for Higgs boson pairs decaying to $\textrm{WWWW}$, $\textrm{WW}\tau\tau$, and $\tau\tau\tau\tau$ in proton-proton collisions at $\sqrt{s} = 13~\mathrm{TeV}$
por: CMS Collaboration
Publicado: (2022)

Measurement of tau polarisation tau --> mu nu-tau nu-mu decays
por: Roehn, S, et al.
Publicado: (1991)

The Tau polarization measurement at LEP and the nature of the $\tau W \nu_{\tau}$ coupling
por: Privitera, P
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_dvdosk997mkbceucgsvcoid1b8