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Wanted: more monitoring and control during inclusion body processing

Inclusion bodies (IBs) are insoluble aggregates of misfolded protein in Escherichia coli. Against the outdated belief that the production of IBs should be avoided during recombinant protein production, quite a number of recombinant products are currently produced as IBs, which are then processed to...

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Detalles Bibliográficos
Autores principales: Humer, Diana, Spadiut, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208753/
https://www.ncbi.nlm.nih.gov/pubmed/30341583
http://dx.doi.org/10.1007/s11274-018-2541-5