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eNOS expression and NO release during hypoxia is inhibited by miR-200b in human endothelial cells
The nitric oxide (NO) secreted by vascular endothelium is required for the maintenance of cardiovascular homeostasis. Diminished release of NO generated by endothelial NO synthase contributes to endothelial dysfunction. Hypoxia and ischemia reduce endothelial eNOS expression via posttranscriptional...
Autores principales: | Janaszak-Jasiecka, Anna, Siekierzycka, Anna, Bartoszewska, Sylwia, Serocki, Marcin, Dobrucki, Lawrence W., Collawn, James F., Kalinowski, Leszek, Bartoszewski, Rafal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208887/ https://www.ncbi.nlm.nih.gov/pubmed/29737439 http://dx.doi.org/10.1007/s10456-018-9620-y |
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