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The mycotoxin alternariol suppresses lipopolysaccharide-induced inflammation in THP-1 derived macrophages targeting the NF-κB signalling pathway

Alternariol (AOH) is a secondary metabolite formed by black mold of the genus Alternaria alternata. Due to limited hazard and occurrence data, AOH is still considered as an “emerging mycotoxin” and, as such, not monitored and regulated yet. Recent studies indicate immunosuppressive effects in vitro...

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Detalles Bibliográficos
Autores principales: Kollarova, Jessica, Cenk, Ebru, Schmutz, Cornelia, Marko, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208963/
https://www.ncbi.nlm.nih.gov/pubmed/30175388
http://dx.doi.org/10.1007/s00204-018-2299-4