Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria

Succinate-driven reverse electron transport (RET) is one of the main sources of mitochondrial reactive oxygen species (mtROS) in ischemia-reperfusion injury. RET is dependent on mitochondrial membrane potential (Δψ(m)) and transmembrane pH difference (ΔpH), components of the proton motive force (pmf...

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Detalles Bibliográficos
Autores principales: Komlódi, Tímea, Geibl, Fanni F., Sassani, Matilde, Ambrus, Attila, Tretter, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209044/
https://www.ncbi.nlm.nih.gov/pubmed/30116920
http://dx.doi.org/10.1007/s10863-018-9766-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209044/
https://www.ncbi.nlm.nih.gov/pubmed/30116920
http://dx.doi.org/10.1007/s10863-018-9766-8

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