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Astrocyte expression of the Drosophila TNF-alpha homologue, Eiger, regulates sleep in flies

Sleep contributes to cognitive functioning and is sufficient to alter brain morphology and function. However, mechanisms underlying sleep regulation remain poorly understood. In mammals, tumor necrosis factor-alpha (TNFα) is known to regulate sleep, and cytokine expression may represent an evolution...

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Detalles Bibliográficos
Autores principales: Vanderheyden, William M., Goodman, Alan G., Taylor, Rebecca H., Frank, Marcos G., Van Dongen, Hans P. A., Gerstner, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209136/
https://www.ncbi.nlm.nih.gov/pubmed/30379810
http://dx.doi.org/10.1371/journal.pgen.1007724