Cycles of myofiber degeneration and regeneration lead to remodeling of the neuromuscular junction in two mammalian models of Duchenne muscular dystrophy

Mice lacking the sarcolemmal protein dystrophin, designated mdx, have been widely used as a model of Duchenne muscular dystrophy. Dystrophic mdx mice as they mature develop notable morphological abnormalities to their neuromuscular junctions, the peripheral cholinergic synapses responsible for activ...

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Detalles Bibliográficos
Autores principales: Haddix, Seth G., Lee, Young il, Kornegay, Joe N., Thompson, Wesley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209224/
https://www.ncbi.nlm.nih.gov/pubmed/30379896
http://dx.doi.org/10.1371/journal.pone.0205926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209224/
https://www.ncbi.nlm.nih.gov/pubmed/30379896
http://dx.doi.org/10.1371/journal.pone.0205926

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