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Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells

Recent findings point to a role of Checkpoint Inhibitor (CPI) receptors at the tissue level in immune homeostasis. Here we investigated the role of CPI molecules on immune cells in relation to cardiac function. Participants recruited in Chennai, India consisted of HIV+ ART naive viremic (Gp1 n = 102...

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Detalles Bibliográficos
Autores principales: Pallikkuth, Suresh, Pahwa, Rajendra, Kausalya, Bagavathi, Saravanan, Shanmugam, Pan, Li, Vignesh, R., Iqbal, Syed, Solomon, Sunil S., Murugavel, Kailapuri G., Poongulali, Selvamuthu, Kumarasamy, Nagalingeswaran, Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209232/
https://www.ncbi.nlm.nih.gov/pubmed/30379878
http://dx.doi.org/10.1371/journal.pone.0206256