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Increased DNA methylation of SLFN12 in CD4(+) and CD8(+) T cells from multiple sclerosis patients

DNA methylation is an epigenetic mark that is influenced by environmental factors and is associated with changes to gene expression and phenotypes. It may link environmental exposures to disease etiology or indicate important gene pathways involved in disease pathogenesis. We identified genomic regi...

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Detalles Bibliográficos
Autores principales: Rhead, Brooke, Brorson, Ina S., Berge, Tone, Adams, Cameron, Quach, Hong, Moen, Stine Marit, Berg-Hansen, Pål, Celius, Elisabeth Gulowsen, Sangurdekar, Dipen P., Bronson, Paola G., Lea, Rodney A., Burnard, Sean, Maltby, Vicki E., Scott, Rodney J., Lechner-Scott, Jeannette, Harbo, Hanne F., Bos, Steffan D., Barcellos, Lisa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209300/
https://www.ncbi.nlm.nih.gov/pubmed/30379917
http://dx.doi.org/10.1371/journal.pone.0206511