Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

[Image: see text] In this study we investigated lipolysis-triggered supersaturation and precipitation of a set of model compounds formulated in lipid-based formulations (LBFs). The purpose was to explore the relationship between precipitated solid form and inherent physicochemical properties of the...

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Detalles Bibliográficos
Autores principales: Alskär, Linda C., Keemink, Janneke, Johannesson, Jenny, Porter, Christopher J. H., Bergström, Christel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209313/
https://www.ncbi.nlm.nih.gov/pubmed/30142268
http://dx.doi.org/10.1021/acs.molpharmaceut.8b00699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209313/
https://www.ncbi.nlm.nih.gov/pubmed/30142268
http://dx.doi.org/10.1021/acs.molpharmaceut.8b00699

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