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Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
[Image: see text] In this study we investigated lipolysis-triggered supersaturation and precipitation of a set of model compounds formulated in lipid-based formulations (LBFs). The purpose was to explore the relationship between precipitated solid form and inherent physicochemical properties of the...
Autores principales: | Alskär, Linda C., Keemink, Janneke, Johannesson, Jenny, Porter, Christopher J. H., Bergström, Christel A. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209313/ https://www.ncbi.nlm.nih.gov/pubmed/30142268 http://dx.doi.org/10.1021/acs.molpharmaceut.8b00699 |
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