Lynx1 Prevents Long-Term Potentiation Blockade and Reduction of Neuromodulator Expression Caused by Aβ1-42 and JNK Activation

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels. Many neurodegenerative diseases are accompanied by cognitive impairment associated with the dysfunction of nAChRs. The human membrane-tethered prototoxin Lynx1 modulates nAChR function in the brain areas responsible for learni...

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Detalles Bibliográficos
Autores principales: Bychkov, M. L., Vasilyeva, N. A., Shulepko, M. A., Balaban, P. M., Kirpichnikov, M. P., Lyukmanova, E. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209405/
https://www.ncbi.nlm.nih.gov/pubmed/30397527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209405/
https://www.ncbi.nlm.nih.gov/pubmed/30397527

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