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Knockdown of p66Shc Alters Lineage-Associated Transcription Factor Expression in Mouse Blastocysts

The p66Shc adaptor protein regulates apoptosis and senescence during early mammalian development. However, p66Shc expression during mouse preimplantation development is upregulated at the blastocyst stage. Our objective was to determine the biological function of p66Shc during mouse blastocyst devel...

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Detalles Bibliográficos
Autores principales: Edwards, Nicole A., Watson, Andrew J., Betts, Dean H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209429/
https://www.ncbi.nlm.nih.gov/pubmed/30091687
http://dx.doi.org/10.1089/scd.2018.0131