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Mitochondria-lysosome contacts regulate mitochondrial fission via Rab7 GTP hydrolysis

Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and dysfunction of both organelles has been observed in multiple diseases(1–4). Mitochondria are highly dynamic and undergo fission and fusion to maintain a functional mitochondrial network, which drives cellular met...

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Detalles Bibliográficos
Autores principales: Wong, Yvette C., Ysselstein, Daniel, Krainc, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209448/
https://www.ncbi.nlm.nih.gov/pubmed/29364868
http://dx.doi.org/10.1038/nature25486