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Epigenetic Control of Endocrine Pancreas Differentiation in vitro: Current Knowledge and Future Perspectives
The raising worldwide prevalence of Type 1 and Type 2 diabetes mellitus (T1DM and T2DM) solicits the derivation of in vitro methods yielding mature and fully functional β-cells to be used in regenerative medicine. Several protocols to differentiate human embryonic stem cells (hESCs) and induced plur...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209628/ https://www.ncbi.nlm.nih.gov/pubmed/30410880 http://dx.doi.org/10.3389/fcell.2018.00141 |