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Harnessing the Induction of CD8(+) T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells
Cytotoxic CD8(+) T-cells are key players of the immune responses against viruses. During the priming of a CD8(+) T-cell response, the activation of a naïve T-cell by a professional antigen presenting cell (APC) involves the induction of various intracellular and metabolic pathways. The modulation of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209652/ https://www.ncbi.nlm.nih.gov/pubmed/30410483 http://dx.doi.org/10.3389/fimmu.2018.02372 |