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Harnessing the Induction of CD8(+) T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells

Cytotoxic CD8(+) T-cells are key players of the immune responses against viruses. During the priming of a CD8(+) T-cell response, the activation of a naïve T-cell by a professional antigen presenting cell (APC) involves the induction of various intracellular and metabolic pathways. The modulation of...

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Detalles Bibliográficos
Autores principales: Nicoli, Francesco, Paul, Stéphane, Appay, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209652/
https://www.ncbi.nlm.nih.gov/pubmed/30410483
http://dx.doi.org/10.3389/fimmu.2018.02372