Cargando…

Harnessing the Induction of CD8(+) T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells

Cytotoxic CD8(+) T-cells are key players of the immune responses against viruses. During the priming of a CD8(+) T-cell response, the activation of a naïve T-cell by a professional antigen presenting cell (APC) involves the induction of various intracellular and metabolic pathways. The modulation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nicoli, Francesco, Paul, Stéphane, Appay, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209652/ https://www.ncbi.nlm.nih.gov/pubmed/30410483 http://dx.doi.org/10.3389/fimmu.2018.02372

Ejemplares similares

Naïve CD8(+) T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8(+) T-Cells
por: Nicoli, Francesco, et al.
Publicado: (2018)

Impaired Priming of SARS-CoV-2-Specific Naive CD8(+) T Cells in Older Subjects
por: Gallerani, Eleonora, et al.
Publicado: (2021)

Harnessing CD8(+) T Cells Under HIV Antiretroviral Therapy
por: Warren, Joanna A., et al.
Publicado: (2019)

Hepatitis B surface antigen reduction is associated with hepatitis B core-specific CD8(+) T cell quality
por: Takahama, Shokichi, et al.
Publicado: (2023)

The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8(+) T-cell responses in vitro
por: Papagno, Laura, et al.
Publicado: (2020)

Microglia and Perivascular Macrophages Act as Antigen Presenting Cells to Promote CD8 T Cell Infiltration of the Brain
por: Goddery, Emma N., et al.
Publicado: (2021)

Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells
por: Kunkl, Martina, et al.
Publicado: (2023)

Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells
por: Haddadi, Siamak, et al.
Publicado: (2019)

Induction of broad multifunctional CD8+ and CD4+ T cells by hepatitis B virus antigen-based synthetic long peptides ex vivo
por: Jansen, Diahann T. S. L., et al.
Publicado: (2023)

Palmitoylated antigens for the induction of anti-tumor CD8(+) T cells and enhanced tumor recognition
por: Stolk, Dorian A., et al.
Publicado: (2021)

Corrigendum: Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells
por: Kunkl, Martina, et al.
Publicado: (2023)

Nanoparticles Engineered as Artificial Antigen-Presenting Cells Induce Human CD4(+) and CD8(+) Tregs That Are Functional in Humanized Mice
por: Giang, Sophia, et al.
Publicado: (2021)

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8(+) T Cell Tolerance Development
por: Damo, Martina, et al.
Publicado: (2021)

CXCR5+ CD8 T Cells: Protective or Pathogenic?
por: Valentine, Kristen M., et al.
Publicado: (2019)

Liposomal Elongation Factor-1α Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis
por: Sabur, Abdus, et al.
Publicado: (2018)

Antigen presentation by clonally diverse CXCR5+ B cells to CD4 and CD8 T cells is associated with durable response to immune checkpoint inhibitors
por: Ding, Lizhong, et al.
Publicado: (2023)

A Novel Method Linking Antigen Presentation by Human Monocyte-Derived Macrophages to CD8(+) T Cell Polyfunctionality
por: Short, Kirsty R., et al.
Publicado: (2013)

CD8+ T-Cell Repertoire in Human Leukocyte Antigen Class I-Mismatched Alloreactive Immune Response
por: Bettens, Florence, et al.
Publicado: (2021)

The Antigen Presenting Potential of CD21(low) B Cells
por: Reincke, Marlene E., et al.
Publicado: (2020)

Professional antigen presenting cells in human herpesvirus 8 infection
por: Knowlton, Emilee R., et al.
Publicado: (2013)

Harnessing Dendritic Cells for Tumor Antigen Presentation
por: Nierkens, Stefan, et al.
Publicado: (2011)

IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients
por: Tilly, Gaëlle, et al.
Publicado: (2017)

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8(+) T cells in HIV infection
por: Cabral-Piccin, Mariela P., et al.
Publicado: (2023)

Effects of hypoxia on antigen presentation and T cell-based immune recognition of HPV16-transformed cells
por: Mohan, Nitya, et al.
Publicado: (2022)

Alloactivation of Naïve CD4(+)CD8(−)CD25(+)T Regulatory Cells: Expression of CD8α Identifies Potent Suppressor Cells That Can Promote Transplant Tolerance Induction
por: Verma, Nirupama D., et al.
Publicado: (2019)

Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation
por: Saas, Philippe, et al.
Publicado: (2022)

Pathogenic CD8 T Cells in Multiple Sclerosis and Its Experimental Models
por: Huseby, Eric S., et al.
Publicado: (2012)

The Potential of Harnessing IL-2-Mediated Immunosuppression to Prevent Pathogenic B Cell Responses
por: Papillion, Amber, et al.
Publicado: (2021)

Cognate Antigen Stimulation Generates Potent CD8(+) Inflammatory Effector T Cells
por: Sung, Hsueh-Cheng, et al.
Publicado: (2013)

Priming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite Antigens
por: Corradin, Giampietro, et al.
Publicado: (2014)

Human Macrophages Escape Inhibition of Major Histocompatibility Complex-Dependent Antigen Presentation by Cytomegalovirus and Drive Proliferation and Activation of Memory CD4(+) and CD8(+) T Cells
por: Frascaroli, Giada, et al.
Publicado: (2018)

Mast Cells Modulate Antigen-Specific CD8(+) T Cell Activation During LCMV Infection
por: Hackler, Yana, et al.
Publicado: (2021)

CD83: Activation Marker for Antigen Presenting Cells and Its Therapeutic Potential
por: Li, Ziduo, et al.
Publicado: (2019)

An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8(+) T Cells
por: Wang, Wei, et al.
Publicado: (2017)

Vaccine-Induced CD8(+) T Cell Responses in Children: A Review of Age-Specific Molecular Determinants Contributing to Antigen Cross-Presentation
por: Beijnen, Elisabeth M. S., et al.
Publicado: (2020)

HLA-Class II Artificial Antigen Presenting Cells in CD4(+) T Cell-Based Immunotherapy
por: Couture, Alexandre, et al.
Publicado: (2019)

Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition
por: Wildner, Nils H., et al.
Publicado: (2022)

Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes
por: Schmidt, Julien, et al.
Publicado: (2013)

Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens
por: Zhao, Yuan, et al.
Publicado: (2012)

The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition
por: Eccleston, R. Charlotte, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u15kvdmf3k21g8bilclje63naf