TRIM21 Restricts Coxsackievirus B3 Replication, Cardiac and Pancreatic Injury via Interacting With MAVS and Positively Regulating IRF3-Mediated Type-I Interferon Production

Tripartite motif-containing 21 (TRIM21) is a regulator of tissue inflammation and pro-inflammatory cytokine production, and has been implicated in negative regulation of IRF3-dependent type I interferon signaling. However, the antiviral activity of TRIM21 varies among diverse viruses and its role on...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Li, Min, Song, Yahui, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209670/
https://www.ncbi.nlm.nih.gov/pubmed/30410495
http://dx.doi.org/10.3389/fimmu.2018.02479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209670/
https://www.ncbi.nlm.nih.gov/pubmed/30410495
http://dx.doi.org/10.3389/fimmu.2018.02479

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