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Inositol-6 phosphate inhibits the mTOR pathway and induces autophagy-mediated death in HT-29 colon cancer cells

INTRODUCTION: Colorectal cancer (CRC) is common, with a worldwide incidence estimated at more than 1 million cases annually. Therefore, the search for agents for CRC treatment is highly warranted. Inositol-6 phosphate (IP(6)) is enriched in rice bran and possesses many beneficial effects. In the pre...

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Detalles Bibliográficos
Autores principales: Pandurangan, Ashok Kumar, Ismail, Salmiah, Esa, Norhaizan Mohd, Munusamy, Murugan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209706/
https://www.ncbi.nlm.nih.gov/pubmed/30393482
http://dx.doi.org/10.5114/aoms.2018.76935