Role of Osteocytes in Myeloma Bone Disease: Anti-sclerostin Antibody as New Therapeutic Strategy

Osteocytes are terminally differentiated cells of the osteoblast lineage. They are involved in the regulation of bone remodeling by increasing osteoclast formation or decreasing bone formation by the secretion of the osteoblast inhibitor sclerostin. Monoclonal antibody anti-sclerostin, Romosozumab,...

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Detalles Bibliográficos
Autores principales: Toscani, Denise, Bolzoni, Marina, Ferretti, Marzia, Palumbo, Carla, Giuliani, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209728/
https://www.ncbi.nlm.nih.gov/pubmed/30410490
http://dx.doi.org/10.3389/fimmu.2018.02467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209728/
https://www.ncbi.nlm.nih.gov/pubmed/30410490
http://dx.doi.org/10.3389/fimmu.2018.02467

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