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Impact of PD‐L1, transforming growth factor‐β expression and tumor‐infiltrating CD8(+) T cells on clinical outcome of patients with advanced thymic epithelial tumors
BACKGROUND: Advanced thymic epithelial tumors (TETs) are indolent and poorly responsive to chemotherapy. PD‐1/PD‐L1 inhibitors have shown remarkable clinical benefit in several cancers; however, many immunomodulatory molecules have been identified that affect the immune response. This study examined...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209778/ https://www.ncbi.nlm.nih.gov/pubmed/30168897 http://dx.doi.org/10.1111/1759-7714.12826 |