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Impact of PD‐L1, transforming growth factor‐β expression and tumor‐infiltrating CD8(+) T cells on clinical outcome of patients with advanced thymic epithelial tumors

BACKGROUND: Advanced thymic epithelial tumors (TETs) are indolent and poorly responsive to chemotherapy. PD‐1/PD‐L1 inhibitors have shown remarkable clinical benefit in several cancers; however, many immunomodulatory molecules have been identified that affect the immune response. This study examined...

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Detalles Bibliográficos
Autores principales: Duan, Jianchun, Liu, Xidong, Chen, Han, Sun, Yu, Liu, Yiqiang, Bai, Hua, Wang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209778/
https://www.ncbi.nlm.nih.gov/pubmed/30168897
http://dx.doi.org/10.1111/1759-7714.12826