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Pathologic Replication-Independent Endogenous DNA Double-Strand Breaks Repair Defect in Chronological Aging Yeast

Reduction of physiologic replication-independent endogenous DNA double strand breaks (Phy-RIND-EDSBs) in chronological aging yeast increases pathologic RIND-EDSBs (Path-RIND-EDSBs). Path-RIND-EDSBs can occur spontaneously in non-dividing cells without any inductive agents, and they must be repaired...

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Detalles Bibliográficos
Autores principales: Pongpanich, Monnat, Patchsung, Maturada, Mutirangura, Apiwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209823/
https://www.ncbi.nlm.nih.gov/pubmed/30410502
http://dx.doi.org/10.3389/fgene.2018.00501