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Lack of Antidepressant Effects of Low-Voltage-Sensitive T-Type Calcium Channel Blocker Ethosuximide in a Chronic Social Defeat Stress Model: Comparison with (R)-Ketamine

BACKGROUND: A recent study demonstrated that low-voltage-sensitive T-type calcium channel blocker ethosuximide shows rapid antidepressant actions. This study was conducted to compare the antidepressant actions of ethosuximide and (R)-ketamine in a chronic social defeat stress model. METHODS: Ethosux...

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Detalles Bibliográficos
Autores principales: Tian, Zheng, Dong, Chao, Zhang, Kai, Chang, Lijia, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209850/
https://www.ncbi.nlm.nih.gov/pubmed/30085247
http://dx.doi.org/10.1093/ijnp/pyy072