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Maternal Deprivation Enhances Contextual Fear Memory via Epigenetically Programming Second-Hit Stress-Induced Reelin Expression in Adult Rats

BACKGROUND: Early-life stress increases the risk for posttraumatic stress disorder. However, the epigenetic mechanism of early-life stress-induced susceptibility to posttraumatic stress disorder in adulthood remains unclear. METHODS: Rat pups were exposed to maternal deprivation during postnatal day...

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Detalles Bibliográficos
Autores principales: Wang, Run-Hua, Chen, Ye-Fei, Chen, Si, Hao, Bo, Xue, Li, Wang, Xiao-Guang, Shi, Yan-Wei, Zhao, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209857/
https://www.ncbi.nlm.nih.gov/pubmed/30169690
http://dx.doi.org/10.1093/ijnp/pyy078