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Maternal Deprivation Enhances Contextual Fear Memory via Epigenetically Programming Second-Hit Stress-Induced Reelin Expression in Adult Rats
BACKGROUND: Early-life stress increases the risk for posttraumatic stress disorder. However, the epigenetic mechanism of early-life stress-induced susceptibility to posttraumatic stress disorder in adulthood remains unclear. METHODS: Rat pups were exposed to maternal deprivation during postnatal day...
Autores principales: | Wang, Run-Hua, Chen, Ye-Fei, Chen, Si, Hao, Bo, Xue, Li, Wang, Xiao-Guang, Shi, Yan-Wei, Zhao, Hu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209857/ https://www.ncbi.nlm.nih.gov/pubmed/30169690 http://dx.doi.org/10.1093/ijnp/pyy078 |
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