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Adult Cellular Neuroadaptations Induced by Adolescent THC Exposure in Female Rats Are Rescued by Enhancing Anandamide Signaling

BACKGROUND: In rodent models, chronic exposure to cannabis’ psychoactive ingredient, Δ(9)-tetrahydrocannabinol, during adolescence leads to abnormal behavior in adulthood. In female rats, this maladaptive behavior is characterized by endophenotypes for depressive-like and psychotic-like disorders as...

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Detalles Bibliográficos
Autores principales: Cuccurazzu, Bruna, Zamberletti, Erica, Nazzaro, Cristiano, Prini, Pamela, Trusel, Massimo, Grilli, Mariagrazia, Parolaro, Daniela, Tonini, Raffaella, Rubino, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209859/
https://www.ncbi.nlm.nih.gov/pubmed/29982505
http://dx.doi.org/10.1093/ijnp/pyy057