Oncobox Bioinformatical Platform for Selecting Potentially Effective Combinations of Target Cancer Drugs Using High-Throughput Gene Expression Data

Sequential courses of anticancer target therapy lead to selection of drug-resistant cells, which results in continuous decrease of clinical response. Here we present a new approach for predicting effective combinations of target drugs, which act in a synergistic manner. Synergistic combinations of d...

Descripción completa

Detalles Bibliográficos
Autores principales: Sorokin, Maxim, Kholodenko, Roman, Suntsova, Maria, Malakhova, Galina, Garazha, Andrew, Kholodenko, Irina, Poddubskaya, Elena, Lantsov, Dmitriy, Stilidi, Ivan, Arhiri, Petr, Osipov, Andreyan, Buzdin, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209915/
https://www.ncbi.nlm.nih.gov/pubmed/30274248
http://dx.doi.org/10.3390/cancers10100365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209915/
https://www.ncbi.nlm.nih.gov/pubmed/30274248
http://dx.doi.org/10.3390/cancers10100365

Ejemplares similares