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Oncobox Bioinformatical Platform for Selecting Potentially Effective Combinations of Target Cancer Drugs Using High-Throughput Gene Expression Data
Sequential courses of anticancer target therapy lead to selection of drug-resistant cells, which results in continuous decrease of clinical response. Here we present a new approach for predicting effective combinations of target drugs, which act in a synergistic manner. Synergistic combinations of d...
Autores principales: | Sorokin, Maxim, Kholodenko, Roman, Suntsova, Maria, Malakhova, Galina, Garazha, Andrew, Kholodenko, Irina, Poddubskaya, Elena, Lantsov, Dmitriy, Stilidi, Ivan, Arhiri, Petr, Osipov, Andreyan, Buzdin, Anton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209915/ https://www.ncbi.nlm.nih.gov/pubmed/30274248 http://dx.doi.org/10.3390/cancers10100365 |
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