Folding of G(α) Subunits: Implications for Disease States

[Image: see text] G-proteins play a central role in signal transduction by fluctuating between “on” and “off” phases that are determined by a conformational change. cAMP is a secondary messenger whose formation is inhibited or stimulated by activated G(iα1) or G(sα) subunit. We used tryptophan fluor...

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Detalles Bibliográficos
Autores principales: Najor, Matthew, Leverson, Brian D., Goossens, Jesse L., Kothawala, Saad, Olsen, Kenneth W., Mota de Freitas, Duarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210069/
https://www.ncbi.nlm.nih.gov/pubmed/30411001
http://dx.doi.org/10.1021/acsomega.8b01174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210069/
https://www.ncbi.nlm.nih.gov/pubmed/30411001
http://dx.doi.org/10.1021/acsomega.8b01174

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