Cargando…
Folding of G(α) Subunits: Implications for Disease States
[Image: see text] G-proteins play a central role in signal transduction by fluctuating between “on” and “off” phases that are determined by a conformational change. cAMP is a secondary messenger whose formation is inhibited or stimulated by activated G(iα1) or G(sα) subunit. We used tryptophan fluor...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210069/ https://www.ncbi.nlm.nih.gov/pubmed/30411001 http://dx.doi.org/10.1021/acsomega.8b01174 |