DYRK1A Protein, A Promising Therapeutic Target to Improve Cognitive Deficits in Down Syndrome

Down syndrome (DS) caused by a trisomy of chromosome 21 (HSA21), is the most common genetic developmental disorder, with an incidence of 1 in 800 live births. Its phenotypic characteristics include intellectual impairment, early onset of Alzheimer’s disease, congenital heart disease, hypotonia, musc...

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Detalles Bibliográficos
Autores principales: Feki, Anis, Hibaoui, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210095/
https://www.ncbi.nlm.nih.gov/pubmed/30332747
http://dx.doi.org/10.3390/brainsci8100187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210095/
https://www.ncbi.nlm.nih.gov/pubmed/30332747
http://dx.doi.org/10.3390/brainsci8100187

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