Sensitization of Cancer Cells to Radiation and Topoisomerase I Inhibitor Camptothecin Using Inhibitors of PARP and Other Signaling Molecules

Radiation and certain anticancer drugs damage DNA, resulting in apoptosis induction in cancer cells. Currently, the major limitations on the efficacy of such therapies are development of resistance and adverse side effects. Sensitization is an important strategy for increasing therapeutic efficacy w...

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Detalles Bibliográficos
Autores principales: Matsuno, Yusuke, Hyodo, Mai, Fujimori, Haruka, Shimizu, Atsuhiro, Yoshioka, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210148/
https://www.ncbi.nlm.nih.gov/pubmed/30274183
http://dx.doi.org/10.3390/cancers10100364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210148/
https://www.ncbi.nlm.nih.gov/pubmed/30274183
http://dx.doi.org/10.3390/cancers10100364

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