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Viral Persistence and Chronicity in Hepatitis C Virus Infection: Role of T-Cell Apoptosis, Senescence and Exhaustion

Hepatitis C virus (HCV) represents a challenging global health threat to ~200 million infected individuals. Clinical data suggest that only ~10–15% of acutely HCV-infected individuals will achieve spontaneous viral clearance despite exuberant virus-specific immune responses, which is largely attribu...

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Detalles Bibliográficos
Autores principales: Barathan, Muttiah, Mohamed, Rosmawati, Yong, Yean K., Kannan, Meganathan, Vadivelu, Jamuna, Saeidi, Alireza, Larsson, Marie, Shankar, Esaki Muthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210370/
https://www.ncbi.nlm.nih.gov/pubmed/30322028
http://dx.doi.org/10.3390/cells7100165