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Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets

The cellular kinases inhibitory-κB kinase (IKK) α and Nuclear Factor-κB (NF-κB)-inducing kinase (NIK) are well recognised as key central regulators and drivers of the non-canonical NF-κB cascade and as such dictate the initiation and development of defined transcriptional responses associated with t...

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Detalles Bibliográficos
Autores principales: Paul, Andrew, Edwards, Joanne, Pepper, Christopher, Mackay, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210445/
https://www.ncbi.nlm.nih.gov/pubmed/30347849
http://dx.doi.org/10.3390/cells7100176